According to newly published research, a new form of double therapy combining a traditional chemotherapy agent with targeted therapy could benefit patients with glioblastoma multiforme, although thus far studies have only been performed in vitro (on lab mice and on cells).
The treatment, investigated by researchers from the University of Massachusetts Medical School, involves the most commonly used chemotherapy drug, temozolomide, in combination with a targeted treatment, in this case a so-called Notch inhibitor.
A Notch inhibitor is a drug that inhibits or blocks the Notch signaling pathway, a pathway believed to be over-expressed in both glioma tissue as well as tumor cells.
CANCER TYPE(S)
Glioblastoma (brain cancer)
TREATMENT TYPE(S)
Combination chemotherapy and a targeted therapy
WHERE WAS THIS RESEARCH PUBLISHED?
Cancer Research
By Ross Bonander
Source
EurekAlert
